MonoMac6 (MM6) cells proteomics LC-MS/MS

ABSTRACT: MicroRNAs (miRs) are small non-coding RNAs, which control the expression of target genes by either translational repression or RNA degradation, known as canonical miR function. MiR-328 has a non-canonical function and can activate gene expression by antagonizing the activity of heterogeneous ribonuclear protein E2 (hnRNP E2). The global importance of such non-canonical miR function is not yet known. In order to achieve a better understanding of the non-canonical miR activity, a compartment specific tandem mass tag (TMT)-based proteomic analysis in differentiated MonoMac6 (MM6) cells was performed.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Cell Culture

SUBMITTER: Elena Ossipova  

LAB HEAD: Per-Johan Jakobsson

PROVIDER: PXD013106 | Pride | 2019-11-27

REPOSITORIES: Pride