Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Hepatocyte, Liver
DISEASE(S): Liver Cancer
SUBMITTER: YA LIU
LAB HEAD: Fenyong Sun
PROVIDER: PXD013143 | Pride | 2019-09-11
REPOSITORIES: Pride
Liu Ya Y Zhang Xiao X Lin Jiafei J Chen Yuxin Y Qiao Yongxia Y Guo Susu S Yang Yueyue Y Zhu Guoqing G Pan Qiuhui Q Wang Jiayi J Sun Fenyong F
Cell death & disease 20190909 9
Although Yes-associated protein (YAP) is very important to liver cancer, its nuclear localisation prevents consideration as a promising therapeutic target and a diagnostic biomarker. Recently, we reported that the protumourigenic roles of YAP in liver cancer are indispensable for transcription factor CP2 (TFCP2) in a Hippo-independent manner; however, proteins that act upstream to simultaneously control YAP and TFCP2 remain unclear. The aim of this study was to uncover such proteins and evaluate ...[more]