Proteomics

Dataset Information

0

In-depth proteomic analysis of nasal secretions from chronic rhinosinusitis and nasal polyps


ABSTRACT: Considering the complex and multifarious features of Chronic rhinosinusitis (CRS) including immunologic patterns, novel modalities are needed to reflect clinical and pathophysiological endotypes beyond nasal polyps.We aimed to investigate the proteome of nasal secretions on filter paper from CRS patients to characterize endotypes.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Nasal Polyp

SUBMITTER: Dohyun Han  

LAB HEAD: Dohyun Han

PROVIDER: PXD013330 | Pride | 2019-07-29

REPOSITORIES: Pride

altmetric image

Publications

In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps.

Kim Yi Sook YS   Han Dohyun D   Kim JinYoup J   Kim Dae Woo DW   Kim Yong Min YM   Mo Ji Hun JH   Choi Hyo Geun HG   Park Jong Wan JW   Shin Hyun Woo HW  

Allergy, asthma & immunology research 20190901 5


<h4>Purpose</h4>Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is inadequate. Therefore, we collected patient nasal secretions on filter paper and characterized the proteomes.<h4>Methods</h4>We performed liquid chromatography-mass spectrometry (MS)/MS in the data-dependent acquisition (DDA) and data-independent acquisition (DI  ...[more]

Similar Datasets

2021-09-09 | PXD018960 | Pride
| E-GEOD-7002 | biostudies-arrayexpress
| E-MTAB-12345 | biostudies-arrayexpress
| E-GEOD-69093 | biostudies-arrayexpress
| E-MTAB-6613 | biostudies-arrayexpress
| E-MTAB-7962 | biostudies-arrayexpress
| E-GEOD-52505 | biostudies-arrayexpress
| E-GEOD-42394 | biostudies-arrayexpress
2016-05-26 | PXD004144 | Pride
| E-GEOD-46567 | biostudies-arrayexpress