Simple targeted assays for metabolic pathways and signaling: a powerful tool for targeted proteomics

ABSTRACT: We introduce STAMPS, a pathway centric web service for the development of targeted proteomics assays. STAMPS guides the user by providing several intuitive interfaces for a rapid and simplified method design. Applying our curated framework to signaling and metabolic pathways, we reduced average assay development time by a factor of ~150 and revealed that the insulin signaling is actively controlled by protein abundance changes in insulin sensitive and resistance states.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Eye, Spleen, Heart, Blood Platelet, Brain, Lung, Liver, Gut, Fat Body, Kidney

SUBMITTER: Andreas Hentschel  

LAB HEAD: Albert Sickmann

PROVIDER: PXD013343 | Pride | 2021-03-22

REPOSITORIES: Pride