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HiPSCs with different colony morphology

ABSTRACT: Here we characterize the the proteome of iPSCs classified into three morphology groups.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Stem Cell

DISEASE(S): Disease Free

SUBMITTER: Heidrun Vethe

LAB HEAD: Helge Ræder

PROVIDER: PXD013481 | Pride | 2020-05-26

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	YB_P16-9_353_sample_10_3.index	Other
	YB_P16-9_353_sample_10_3.raw	Raw
	YB_P16-9_353_sample_10_4.index	Other
	YB_P16-9_353_sample_10_4.raw	Raw
	YB_P16-9_353_sample_1B.index	Other

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Publications

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability.

Bjørlykke Yngvild Y Søviknes Anne M AM Hoareau Laurence L Vethe Heidrun H Mathisen Andreas F AF Chera Simona S Vaudel Marc M Ghila Luiza M LM Ræder Helge H

Stem cells international 20191118

Human induced pluripotent stem cells (hiPSCs) are of high interest because they can be differentiated into a vast range of different cell types. Ideally, reprogrammed cells should sustain long-term culturing in an undifferentiated state. However, some reprogrammed cell lines represent an unstable state by spontaneously differentiating and changing their cellular phenotype and colony morphology. This phenomenon is not fully understood, and no method is available to predict it reliably. In this st ...[more]

PMID: 31827534

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