Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Str. 168
SUBMITTER: Van Loi Vu
LAB HEAD: Prof. Dr. Haike Antelmann
PROVIDER: PXD013607 | Pride | 2019-12-09
REPOSITORIES: Pride
Antioxidants (Basel, Switzerland) 20191129 12
Garlic plants (<i>Allium sativum</i> L.) produce antimicrobial compounds, such as diallyl thiosulfinate (allicin) and diallyl polysulfanes. Here, we investigated the transcriptome and protein <i>S</i>-thioallylomes under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-positive bacterium <i>Bacillus subtilis</i>. Allicin and DAS4 caused a similar thiol-specific oxidative stress response, protein and DNA damage as revealed by the induction of the OhrR, PerR, Spx, YodB, CatR, HypR, Adh ...[more]