Proteomics

Dataset Information

0

Plasma Proteome for Hepatobiliary Carcinomas


ABSTRACT: This project is to identify plasma glycoprotein markers for hepatobiliary cancers

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Cholangiocarcinoma

SUBMITTER: ChengHsun Ho  

LAB HEAD: ChengHsun Ho

PROVIDER: PXD013629 | Pride | 2019-11-12

REPOSITORIES: Pride

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Publications

Plasma proteome plus site-specific N-glycoprofiling for hepatobiliary carcinomas.

Chang Ting-Tsung TT   Cheng Ji-Hong JH   Tsai Hung-Wen HW   Young Kung-Chia KC   Hsieh Sun-Yuan SY   Ho Cheng-Hsun CH  

The journal of pathology. Clinical research 20190625 3


Hepatobiliary cancer is the third leading cause of cancer death worldwide. Appropriate markers for early diagnosis, monitoring of disease progression, and prediction of postsurgical outcome are still lacking. As the majority of circulating N-glycoproteins are originated from the hepatobiliary system, we sought to explore new markers by assessing the dynamics of N-glycoproteome in plasma samples from patients with hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), or combined HCC and CCA (  ...[more]

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