Name: Proteome-wide Cross-linking mass spectrometry
Keywords: Human

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Proteome-wide Cross-linking mass spectrometry

ABSTRACT: Proteome-wide Cross-linking mass spectrometry on human k562 cell lysate

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Erythrocyte, Bone Marrow

SUBMITTER: Kumar Yugandhar

LAB HEAD: Haiyuan Yu

PROVIDER: PXD013928 | Pride | 2020-01-09

REPOSITORIES: Pride

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MaXLinker: Proteome-wide Cross-link Identifications with High Specificity and Sensitivity.

Yugandhar Kumar K Wang Ting-Yi TY Leung Alden King-Yung AK Lanz Michael Charles MC Motorykin Ievgen I Liang Jin J Shayhidin Elnur Elyar EE Smolka Marcus Bustamante MB Zhang Sheng S Yu Haiyuan H

Molecular & cellular proteomics : MCP 20191215 3

Protein-protein interactions play a vital role in nearly all cellular functions. Hence, understanding their interaction patterns and three-dimensional structural conformations can provide crucial insights about various biological processes and underlying molecular mechanisms for many disease phenotypes. Cross-linking mass spectrometry (XL-MS) has the unique capability to detect protein-protein interactions at a large scale along with spatial constraints between interaction partners. The inceptio ...[more]

PMID: 31839598

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Proteome-wide cross-linking mass spectrometry of human K562 cells

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