Dataset Information

Lysine acetylproteome profiling reveals key acetylated proteins involved in heat shock response in the sea cucumber Apostichopus japonicus

ABSTRACT: Intestine of a total of 9 idividuals was sampled. The individuals were collected from 3 groups: Control (C), Heat stress 6h (HS6h) and Heat stress 48h (HS48h).After protein extraction,trypsin digestion and enrichment of Lys-acetylated peptides, the eluted peptides was applied with LC-MS/MS detection and data analysis.Lysine acetylproteome profiling reveals key acetylated proteins involved in heat shock response in the sea cucumber Apostichopus japonicus

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Stichopus Japonicus (sea Cucumber)

TISSUE(S): Intestine

SUBMITTER: Dongxue Xu

LAB HEAD: Dongxue Xu

PROVIDER: PXD013929 | Pride | 2019-11-12

REPOSITORIES: Pride

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Publications

Lysine Acetylation is an Important Post-Translational Modification that Modulates Heat Shock Response in the Sea Cucumber Apostichopus japonicus.

Xu Dongxue D Wang Xuan X

International journal of molecular sciences 20190909 18

Heat stress (HS) is an important factor for the survival of the marine organism Apostichopus japonicus. Lysine acetylation is a pivotal post-translational modification that modulates diverse physiological processes including heat shock response (HSR). In this study, 4028 lysine acetylation sites in 1439 proteins were identified in A. japonicus by acetylproteome sequencing. A total of 13 motifs were characterized around the acetylated lysine sites. Gene Ontology analysis showed that ...[more]

PMID: 31505730

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Dataset Information

Lysine acetylproteome profiling reveals key acetylated proteins involved in heat shock response in the sea cucumber Apostichopus japonicus

Publications

Lysine Acetylation is an Important Post-Translational Modification that Modulates Heat Shock Response in the Sea Cucumber <i>Apostichopus japonicus</i>.

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