Proteomics

Dataset Information

0

Proteomics profiling of Zika- or HIV-infected moncoytes


ABSTRACT: human primary monocytes purified from 2 healthy blood donors were infected in vitro with Zika virus or HIV for 48 hours. Proteomics profiling of infected versus non infected cells was performed to identify up/down-regulated proteins associated to the infection

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte

DISEASE(S): Zika Virus Congenital Syndrome,Human Immunodeficiency Virus Infectious Disease

SUBMITTER: Francois Delalande  

LAB HEAD: Sarah CIANFERANI

PROVIDER: PXD014002 | Pride | 2019-08-22

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
QE24302FD.raw Raw
QE24308FD.raw Raw
QE24314FD.raw Raw
QE24316FD.raw Raw
QE24336FD.raw Raw
Items per page:
1 - 5 of 18
altmetric image

Publications


Zika virus (ZIKV) invades and persists in the central nervous system (CNS), causing severe neurological diseases. However the virus journey, from the bloodstream to tissues through a mature endothelium, remains unclear. Here, we show that ZIKV-infected monocytes represent suitable carriers for viral dissemination to the CNS using human primary monocytes, cerebral organoids derived from embryonic stem cells, organotypic mouse cerebellar slices, a xenotypic human-zebrafish model, and human fetus b  ...[more]

Similar Datasets

| S-EPMC5790621 | BioStudies
| S-EPMC3098854 | BioStudies
| S-EPMC5086669 | BioStudies
| S-EPMC6873492 | BioStudies
| S-EPMC5520290 | BioStudies
| E-GEOD-56591 | BioStudies
| S-EPMC6034846 | BioStudies
| E-GEOD-61171 | BioStudies
2022-04-04 | PXD027263 | Pride
| S-EPMC8594009 | BioStudies