Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Leishmania Mexicana Mhom/gt/2001/u1103
TISSUE(S): Promastigote
SUBMITTER: Tom Beneke
LAB HEAD: Dr Eva Gluenz
PROVIDER: PXD014077 | Pride | 2020-01-20
REPOSITORIES: Pride
Journal of cell science 20200123 2
Motile eukaryotic flagella beat through coordinated activity of dynein motor proteins; however, the mechanisms of dynein coordination and regulation are incompletely understood. The inner dynein arm (IDA) f complex (also known as the I1 complex), and the tether and tether head (T/TH) complex are thought to be key regulators of dynein action but, unlike the IDA f complex, T/TH proteins remain poorly characterised. Here, we characterised T/TH-associated proteins in the protist <i>Leishmania mexica ...[more]