GRASP Proximity Labeling
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Yu-Hsiu Lin
LAB HEAD: Jayanta Debnath
PROVIDER: PXD014247 | Pride | 2021-10-02
REPOSITORIES: Pride
Publications
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network.
Liu Jennifer Y JY Lin Yu-Hsiu Tony YT Leidal Andrew M AM Huang Hector H HH Ye Jordan J Wiita Arun P AP Debnath Jayanta J
Biology open 20211012 10
There is great interest in understanding the cellular mechanisms controlling autophagy, a tightly regulated catabolic and stress-response pathway. Prior work has uncovered links between autophagy and the Golgi reassembly stacking protein of 55 kDa (GRASP55), but their precise interrelationship remains unclear. Intriguingly, both autophagy and GRASP55 have been functionally and spatially linked to the endoplasmic reticulum (ER)---Golgi interface, broaching this compartment as a site where GRASP55 ...[more]
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