Candida albicans (DAY286 yeast) extracellular vesicle and whole cell lysate proteomes

ABSTRACT: We performed proteomic analysis of extracellular vesicles (EVs) and whole cell lysates (WCL) isolated from the same liquid culture (strain = DAY286, n = 3). This data set is the first label-free quantitative comparative study of the proteins in C. albicans EVs and their parent planktonic (yeast-form) cells. We identified proteins enriched in EVs versus WCL by comparing their LFQ intensities across all samples. After linking these results with EV enrichment data from other strains, we proposed a suite of putative EV marker proteins which were useful for multiple C. albicans strains and morphologies.

INSTRUMENT(S):

ORGANISM(S): Candida Albicans (yeast)

SUBMITTER: Charlotte Dawson  

LAB HEAD: Mark Bleackley

PROVIDER: PXD014367 | Pride | 2020-04-17

REPOSITORIES: Pride