Proteomics

Dataset Information

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Vibrio alginolyticus iTRAQ


ABSTRACT: In recent years, due to the influence of climate change and rising sea temperature, the incidence of Vibrio alginolyticus infections is increasing, and becoming the second most common Vibrio species reported in human illness. Therefore, better understanding of the pathogenic mechanism of V. alginolyticus infection is urgently needed. Vvrr1 (Vibrio virulence regulatory RNA 1) is a new found ncRNA predicted to be closely related to the adhesion ability of V. alginolyticus through the previous RNA-seq. In this study, the target genes of Vvrr1 were fully screened and verified by constructing Vvrr1 over-expressed strains and proteome sequencing technology.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Vibrio alginolyticus  

TISSUE(S): Cell Culture

DISEASE(S): Not Available

SUBMITTER: Lixing Huang  

LAB HEAD: Lixing Huang

PROVIDER: PXD014375 | Pride | 2020-05-26

REPOSITORIES: pride

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Publications

Mechanisms underlying the virulence regulation of new Vibrio alginolyticus ncRNA Vvrr1 with a comparative proteomic analysis.

Zuo Yanfei Y   Zhao Lingmin L   Xu Xiaojin X   Zhang Jiaonan J   Zhang Jiaolin J   Yan Qingpi Q   Huang Lixing L  

Emerging microbes & infections 20190101 1


The incidence of Vibrio alginolyticus infections has increased in recent years due to the influence of climate change and rising sea temperature. Vibrio virulence regulatory RNA 1 (Vvrr1) is a newly found noncoding RNA (ncRNA) predicted to be closely related to the adhesion ability of V. alginolyticus based on the previous RNA-seq. In this study, the target genes of Vvrr1 were fully screened and verified by constructing Vvrr1-overexpressing strains and using the proteome sequencing technology. P  ...[more]

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