TGFβ activity released from platelet-rich fibrin adsorbs to titanium surface and collagen membranes

ABSTRACT: Considering that PRF is clinically used in combination with dental implants and collagen membranes, we exposed titanium discs and collagen membranes to PRF lysates. We showed here that PRF-derived TGF-β activity adsorbs to titanium implants and collagen membranes indicated by the changes in gene expression and immunoassay analysis. Our study points towards TGF-β as major target of PRF and suggest that TGF-β activity released by PRF adsorbs to titanium surface and collagen membranes.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Blood Plasma, Blood Serum, Blood

DISEASE(S): Disease Free

SUBMITTER: Goran Mitulović  

LAB HEAD: Goran MItulović

PROVIDER: PXD014382 | Pride | 2020-06-24

REPOSITORIES: Pride