Dataset Information
Identifying alterations post ILK inhibition in Meningioma cell lines
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell
DISEASE(S): Brain Cancer
SUBMITTER: 
Shuvolina Mukherjee
LAB HEAD: SANJEEVA SRIVASTAVA
PROVIDER: PXD014855 | Pride | 2021-09-08
REPOSITORIES: Pride
Publications
Comprehending Meningioma Signaling Cascades Using Multipronged Proteomics Approaches & Targeted Validation of Potential Markers.
Frontiers in oncology 20200826
Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free quantitative proteome analysis to identifying druggable targets and perturbed pathways for therapeutic intervention. Label-free based proteomics study was done from peptide samples of 21 patients and 8 non-tumor controls which were followed up with Phosphoproteomics to identify the kinases and phosphorylated components o ...[more]
