Identifying alterations post ILK inhibition in Meningioma cell lines

ABSTRACT: The current study reports alterations in PI3-Akt and Focal adhesion pathway post ILK inhibition in meningioma cell lines. The inhibition is done using a pyrazole that specifically inhibits Integrin Link Kinase. The global proteomic profile was analysed post treatment (24 hours) in treated vs untreated cell line replicates.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

DISEASE(S): Brain Cancer

SUBMITTER: Shuvolina Mukherjee  

LAB HEAD: SANJEEVA SRIVASTAVA

PROVIDER: PXD014855 | Pride | 2021-09-08

REPOSITORIES: Pride