Proteomics

Dataset Information

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Conotoxin Exploitation from Conus betulinus


ABSTRACT: Employing Conus betulinus as a representative, we sequenced and assembled the first Conus genome. After integration of multi-omics data, we provide novel insights into the genetic central dogma of conotoxins, assuming a number ratio of ~1:1:10s for genes/transcripts/peptides.

INSTRUMENT(S): TripleTOF 5600, Q Exactive

ORGANISM(S): Conus Betulinus

SUBMITTER: He Yanbin  

LAB HEAD: Qiong shi

PROVIDER: PXD014892 | Pride | 2021-09-08

REPOSITORIES: Pride

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Publications


Although there are various Conus species with publicly available transcriptome and proteome data, no genome assembly has been reported yet. Here, using Chinese tubular cone snail (C. betulinus) as a representative, we sequenced and assembled the first Conus genome with original identification of 133 genome-widely distributed conopeptide genes. After integration of our genomics, transcriptomics, and peptidomics data in the same species, we established a primary genetic central dogma of diverse co  ...[more]

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