Proteomics

Dataset Information

0

Haloferax volcanii_Shotgun_Archaeal Proteome Project


ABSTRACT: Archaea are ubiquitous prokaryotes with a wide range of habitats, important roles in ecology, biotechnology and potentially even human health. Despite that, our understanding of archaeal cell biology is still rather limited, partially because the application of systems biology approaches is lacking behind the other domains of life. Here we introduce/announce the Archaeal Proteome Project (ArcPP), a community effort that aims for the comprehensive analysis of archaeal proteomes. Starting with the model archaeon Haloferax volcanii, we have re-analyzed more than 2 TB of MS result files (>20 Mio. spectra) using state-of-the-art bioinformatic tools, increasing peptide spectrum matches and leading to the secure identification of >3000 proteins. This dataset is part of the Archaeal Proteome Project dataset

INSTRUMENT(S): Q Exactive

ORGANISM(S): Haloferax Volcanii Ds2

TISSUE(S): Cell Line Cell

SUBMITTER: Sébastien Ferreira-Cerca  

LAB HEAD: Sébastien Ferreira-Cerca

PROVIDER: PXD014974 | Pride | 2020-05-11

REPOSITORIES: Pride

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Publications


While many aspects of archaeal cell biology remain relatively unexplored, systems biology approaches like mass spectrometry (MS) based proteomics offer an opportunity for rapid advances. Unfortunately, the enormous amount of MS data generated often remains incompletely analyzed due to a lack of sophisticated bioinformatic tools and field-specific biological expertise for data interpretation. Here we present the initiation of the Archaeal Proteome Project (ArcPP), a community-based effort to comp  ...[more]

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