Interactome of the TCF3-HLF fusion protein

ABSTRACT: Oncogenic chimeric transcription factors are central drivers in cancer. To understand how the TCF3-HLF fusion protein rewires the transcriptional landscape in t(17;19) positive leukemia, functional genetic and proteomic experiments were conducted. In this dataset, the protein-protein interactions of the endogenous TCF3-HLF complex were characterized by AP-MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Fabian Frommelt  

LAB HEAD: Jean-Pierre Bourquin

PROVIDER: PXD014992 | Pride | 2020-08-05

REPOSITORIES: Pride