Dataset Information
Proteomic effects of mIR-877-3p in cervical cancer
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Uterine Cervix
DISEASE(S): Cervix Carcinoma
SUBMITTER: 
Enrique SantamarÃa
LAB HEAD: Enrique Santamaria
PROVIDER: PXD014993 | Pride | 2021-09-08
REPOSITORIES: Pride
Publications
Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix.
Cancers 20210406 7
No therapeutic targets and molecular biomarkers are available in cervical cancer (CC) management. In other cancer types, micro-RNA-877-3p (miR-877-3p) has been associated with events relevant for CC development. Thus, we aimed to determine miR-877-3p role in CC. miR-877-3p levels were examined by quantitative-PCR in 117 cervical lesions and tumors. Effects on CC cell proliferation, migration, and invasion were evaluated upon anti-miR-877-3p transfection. miR-877-3p dependent molecular mechanism ...[more]