CD4+ Th immunogenicity of Ascaris spp.
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human) Ascaris Suum
SUBMITTER: 
Miguel Alvaro
LAB HEAD: Christian Freund
PROVIDER: PXD015012 | Pride | 2020-03-04
REPOSITORIES: Pride
Publications
CD4<sup>+</sup> T<sub>h</sub> immunogenicity of the <i>Ascaris spp</i>. secreted products.
Ebner Friederike F Morrison Eliot E Bertazzon Miriam M Midha Ankur A Hartmann Susanne S Freund Christian C Álvaro-Benito Miguel M
NPJ vaccines 20200320
<i>Ascaris spp</i>. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines. The parasite-secreted products represent the most relevant, yet complex (>250 proteins) antigens of <i>Ascaris spp</i>. as defining the pathogen-host interplay. We applied an in vitro antigen processing system coupled to quantitative proteomics to identify potential CD4<sup>+</sup> T<sub>h</sub> cell epitopes in <i>As ...[more]
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