Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Multipotent Stem Cell, Cell Suspension Culture, Cell Culture
SUBMITTER: Arthur Kopylov
LAB HEAD: Pulin Andrey
PROVIDER: PXD015410 | Pride | 2021-11-15
REPOSITORIES: Pride
Saburina Irina N IN Kosheleva Nastasia V NV Kopylov Arthur T AT Lipina Tatiana V TV Krasina Marina E ME Zurina Irina M IM Gorkun Anastasiya A AA Girina Svetlana S SS Pulin Andrey A AA Kaysheva Anna L AL Morozov Sergey G SG
Proteomics 20211101 3
Myocyte differentiation is featured by adaptation processes, including mitochondria repopulation and cytoskeleton re-organization. The difference between monolayer and spheroid cultured cells at the proteomic level is uncertain. We cultivated alveolar mucosa multipotent mesenchymal stromal cells in spheroids in a myogenic way for the proper conditioning of ECM architecture and cell morphology, which induced spontaneous myogenic differentiation of cells within spheroids. Electron microscopy analy ...[more]