Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human) Botryotinia Fuckeliana (noble Rot Fungus) (botrytis Cinerea) Saccharomyces Cerevisiae (baker's Yeast)
TISSUE(S): Cell Culture
SUBMITTER: Ilaria Piazza
LAB HEAD: Dr. Lukas Reiter and Prof. Dr. Paola Picotti
PROVIDER: PXD015446 | Pride | 2020-09-09
REPOSITORIES: Pride
Nature communications 20200821 1
Chemoproteomics is a key technology to characterize the mode of action of drugs, as it directly identifies the protein targets of bioactive compounds and aids in the development of optimized small-molecule compounds. Current approaches cannot identify the protein targets of a compound and also detect the interaction surfaces between ligands and protein targets without prior labeling or modification. To address this limitation, we here develop LiP-Quant, a drug target deconvolution pipeline based ...[more]