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Proteomic Analysis of Lysine Acetylation and succinylation in pogostemon cablin

ABSTRACT: By the combination of affinity enrichment and high-resolution LC-MS/MS analysis, large-scale lysine acetylome analysis was performed. Altogether, 6,925 lysine acetylation sites in 2,526 protein groups were identified. Intensive bioinformatic analysis was then carried out to annotate those identified lysine acetylated targets in response to drug treatment, including GO annotation, domain annotation, subcellular localization, KEGG pathway annotation, functional cluster analysis, etc. Based on the results, further studies following the lysine acetylome analysis were suggested

INSTRUMENT(S): Q Exactive

ORGANISM(S): Pogostemon Cablin

TISSUE(S): Plant Cell, Leaf

SUBMITTER: Jones Macke

LAB HEAD: Likai Chen

PROVIDER: PXD015567 | Pride | 2019-12-11

REPOSITORIES: Pride

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Global analysis of lysine succinylation in patchouli plant leaves.

Wang Xiaobing X Chen Xiuzhen X Li Junren J Zhou Xuanxuan X Liu Yanting Y Zhong Liting L Tang Yun Y Zheng Hai H Liu Jiyun J Zhan Ruoting R Chen Likai L

Horticulture research 20191201

Lysine succinylation is a novel, naturally occurring posttranslational modification (PTM) in living organisms. Global lysine succinylation identification has been performed at the proteomic level in various species; however, the study of lysine succinylation in plant species is relatively limited. Patchouli plant (<i>P. cablin</i> (Blanco) Benth., Lamiaceae) is a globally important industrial plant and medicinal herb. In the present study, lysine succinylome analysis was carried out in patchouli ...[more]

PMID: 31814986

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