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IDENTIFICATION OF THE CANIDAE IRON REGULATORY HORMONE HEPCIDIN

ABSTRACT: Quantification and characterisation of canine hepcidin by LC-MS

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Blood Serum

SUBMITTER: Martin Mead

LAB HEAD: Joel Gummer

PROVIDER: PXD015661 | Pride | 2020-05-26

REPOSITORIES: Pride

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Identification of The Canidae Iron Regulatory Hormone Hepcidin.

Mead Martin K MK Claus Melissa M Litton Edward E Smart Lisa L Raisis Anthea A Rossi Gabriele G Trengove Robert D RD Gummer Joel P A JPA

Scientific reports 20191218 1

Hepcidins are an evolutionarily conserved class of liver-expressed peptide, from which the twenty-five amino acid hormone, hepcidin-25 (herein hepcidin), has gained significant notoriety as the master regulator of iron homeostasis in mammals. Hepcidin maintains iron homeostasis by controlling the dietary absorption of iron and the mechanisms of recycling cellular iron stores. With the physiological significance of this hormone well established, it has emerged as an informative biomarker. In a co ...[more]

PMID: 31852911

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