Proteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: exosome-like vesicles and microvesicles

ABSTRACT: Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships. Here, we carried out a detailed proteomic analysis of two populations of EVs – exosome like vesicles (ELVs) and microvesicles (MVs) – from Schistosoma mansoni. We profiled the proteins present in these EVs (including external trypsin-liberated peptides, cargo proteins, integral membrane proteins (IMPs) and peripheral membrane proteins (PMPs) using LC-MS/MS.

INSTRUMENT(S):

ORGANISM(S): Schistosoma Mansoni (blood Fluke)

SUBMITTER: Javier Sotillo  

LAB HEAD: Javier Sotillo

PROVIDER: PXD015857 | Pride | 2019-10-17

REPOSITORIES: Pride