Proteomic analysis of dog plateletes and LFQ quantitation
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Equus Caballus (horse)
TISSUE(S): Blood Platelet, Platelet
SUBMITTER: 
Sheng Zhang
LAB HEAD: Sheng Zhang
PROVIDER: PXD015935 | Pride | 2021-09-08
REPOSITORIES: Pride
Publications
The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response.
Cremer Signe E SE Catalfamo James L JL Goggs Robert R Seemann Stefan E SE Kristensen Annemarie T AT Szklanna Paulina B PB Maguire Patricia B PB Brooks Marjory B MB
Research and practice in thrombosis and haemostasis 20201203 1
<h4>Background</h4>Domestic dogs represent a translational animal model to study naturally occurring human disease. Proteomics has emerged as a promising tool for characterizing human platelet pathophysiology; thus a detailed characterization of the core canine activated platelet secretome (CAPS) will enhance utilization of the canine model. The objectives of this study were development of a robust, high throughput, label-free approach for proteomic identification and quantification of the canin ...[more]
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