Protemics of human cell during HHV-6A reactivation
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Bhupesh Kumar Prusty
LAB HEAD: Bhupesh Kumar Prusty
PROVIDER: PXD016211 | Pride | 2020-04-07
REPOSITORIES: Pride
Publications
Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Schreiner Philipp P Harrer Thomas T Scheibenbogen Carmen C Lamer Stephanie S Schlosser Andreas A Naviaux Robert K RK Prusty Bhupesh K BK
ImmunoHorizons 20200423 4
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers. Human herpesvirus (HHV)-6 and HHV-7 are two infectious triggers for which evidence has been growing. To understand possible causative role of HHV-6 in ME/CFS, metabolic and antiviral phenotypes of U2-OS cells were studied with and without chromosomally integrated HHV-6 and with or without virus reactivation using the histone deacetylase inhibitor trichostatin-A. Proteomic analysi ...[more]
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