The mitochondrial CLPXP complex supports the coordination and assembly of mitochondrial and nuclear encoded protein complexes in Arabidopsis thaliana
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)
TISSUE(S): Plant Cell
SUBMITTER: 
Laxmikanth Kollipara
LAB HEAD: Albert Sickmann
PROVIDER: PXD016263 | Pride | 2020-09-14
REPOSITORIES: Pride
Publications
Mitochondrial CLPP2 Assists Coordination and Homeostasis of Respiratory Complexes.
Petereit Jakob J Duncan Owen O Murcha Monika W MW Fenske Ricarda R Cincu Emilia E Cahn Jonathan J Pružinská Adriana A Ivanova Aneta A Kollipara Laxmikanth L Wortelkamp Stefanie S Sickmann Albert A Lee Jiwon J Lister Ryan R Millar A Harvey AH Huang Shaobai S
Plant physiology 20200622 1
Protein homeostasis in eukaryotic organelles and their progenitor prokaryotes is regulated by a series of proteases including the caseinolytic protease (CLPP). CLPP has essential roles in chloroplast biogenesis and maintenance, but the significance of the plant mitochondrial CLPP remains unknown and factors that aid coordination of nuclear- and mitochondrial-encoded subunits for complex assembly in mitochondria await discovery. We generated knockout lines of the single gene for the mitochondrial ...[more]
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