Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Hendrik Weisser
LAB HEAD: Byron Andrews
PROVIDER: PXD016328 | Pride | 2020-03-31
REPOSITORIES: Pride
Wein Samuel S Andrews Byron B Sachsenberg Timo T Santos-Rosa Helena H Kohlbacher Oliver O Kouzarides Tony T Garcia Benjamin A BA Weisser Hendrik H
Nature communications 20200217 1
The field of epitranscriptomics continues to reveal how post-transcriptional modification of RNA affects a wide variety of biological phenomena. A pivotal challenge in this area is the identification of modified RNA residues within their sequence contexts. Mass spectrometry (MS) offers a comprehensive solution by using analogous approaches to shotgun proteomics. However, software support for the analysis of RNA MS data is inadequate at present and does not allow high-throughput processing. Exist ...[more]