Proteomics

Dataset Information

0

The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments.


ABSTRACT: We have found Rab39a to be important in dendritic cells to promote antigen crosspresentation. As Rab39a is a Rab GTPase, we sought to determine how it influenced the contents of phagosomes. Thus we used SILAC using Rab39a CRISPR KO or reconstituted cells to determine phagosomal protein differences using a proteomics based approach.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Dendritic Cell

SUBMITTER: Freidrich Cruz  

LAB HEAD: Kenneth Rock

PROVIDER: PXD016394 | Pride | 2019-12-11

REPOSITORIES: Pride

Similar Datasets

2022-10-20 | PXD034376 | Pride
2023-11-22 | PXD040042 | Pride
2018-06-29 | PXD007885 | Pride
2015-05-05 | E-GEOD-66504 | biostudies-arrayexpress
2019-03-22 | PXD010478 | Pride
2018-05-16 | PXD006909 | Pride
2011-05-01 | E-GEOD-28106 | biostudies-arrayexpress
2011-08-24 | E-GEOD-31564 | biostudies-arrayexpress
2010-04-09 | E-GEOD-15917 | biostudies-arrayexpress
2020-04-27 | PXD015810 | Pride