Name: Human hela cells mitochondrial LC-MS
Keywords: Mitophagy

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Human hela cells mitochondrial LC-MS

ABSTRACT: We extracted mitochondria from Hela cells which were treated with CCCP or DMSO for 2 h. The samples were digested by FAST and peptides were used DIA to analysis.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Kun Meng

LAB HEAD: Kun Meng

PROVIDER: PXD016400 | Pride | 2020-01-29

REPOSITORIES: Pride

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Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.

Meng Kun K Lu Shaohua S Yan Xin X Sun Yue Y Gao Jing J Wang Yang Y Yin Xingfeng X Sun Zhenghua Z He Qing-Yu QY

Journal of proteome research 20200204 3

Mitochondria are involved in many crucial cellular processes. Maintaining healthy mitochondria is essential for cellular homeostasis. Parkin-dependent mitophagy plays an important role in selectively eliminating damaged mitochondria in mammalian cells. However, mechanisms of Parkin-dependent mitophagy remain elusive. In this research, we performed data-independent acquisition-based quantitative mitochondrial proteomics to study the proteomic alterations of carbonyl cyanide <i>m</i>-chlorophenylh ...[more]

PMID: 31975592

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