Dataset Information
Thermal proteome profiling of Escherichia coli mutants
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL1001200000MODEL0072364382
INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive
ORGANISM(S): Escherichia Coli
SUBMITTER: 
Andre Mateus
LAB HEAD: Mikhail M. Savitski
PROVIDER: PXD016589 | Pride | 2020-09-11
REPOSITORIES: Pride
Publications
The functional proteome landscape of Escherichia coli.
Nature 20201209 7838
Recent developments in high-throughput reverse genetics<sup>1,2</sup> have revolutionized our ability to map gene function and interactions<sup>3-6</sup>. The power of these approaches depends on their ability to identify functionally associated genes, which elicit similar phenotypic changes across several perturbations (chemical, environmental or genetic) when knocked out<sup>7-9</sup>. However, owing to the large number of perturbations, these approaches have been limited to growth or morpholo ...[more]
