Characterization of Primary Patient B-cells under Various Stimulation Conditions

ABSTRACT: The goal of this project was to compare the effects of differential stimulation of primary patient B-cells with CD40L, CpG, anti-IgM, and IL4 individually and in combination. Additionally, we observed a phenomenon where anti-IgM+CpG treatment resulted in a lymphoma-like phenotype and sought to compare this treatment regimen to the lymphoma cell line HBL-1.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B Cell, Primary Cell, Cell Culture

DISEASE(S): Lymphoma

SUBMITTER: Joao Paulo  

LAB HEAD: Joao Paulo

PROVIDER: PXD016961 | Pride | 2025-08-21

REPOSITORIES: Pride