Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
TISSUE(S): Cell Culture
SUBMITTER: Clement Potel
LAB HEAD: Eulàlia de Nadal
PROVIDER: PXD017134 | Pride | 2020-05-27
REPOSITORIES: Pride
Viéitez Cristina C Martínez-Cebrián Gerard G Solé Carme C Böttcher René R Potel Clement M CM Savitski Mikhail M MM Onnebo Sara S Fabregat Marc M Shilatifard Ali A Posas Francesc F de Nadal Eulàlia E
Nucleic acids research 20200401 7
Cells have the ability to sense, respond and adapt to environmental fluctuations. Stress causes a massive reorganization of the transcriptional program. Many examples of histone post-translational modifications (PTMs) have been associated with transcriptional activation or repression under steady-state growth conditions. Comparatively less is known about the role of histone PTMs in the cellular adaptive response to stress. Here, we performed high-throughput genetic screenings that provide a nove ...[more]