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Aquatic decomposition and its effects on the bone proteome for forensic applications

ABSTRACT: Methods currently available to estimate the post-mortem submerged interval (PMSI) of cadavers in water suffer from poor accuracy, being mostly based on morphological examination of the remains. Proteins present within bones have recently attracted more attention from researchers interested in the estimation of the post-mortem interval (PMI) in terrestrial environments. Despite the great potential of proteomic methods for PMI estimation, their application to aquatic environments has not yet been explored. In this study, we examined whether four different types of aquatic environment (tap water, saltwater, pond water and chlorinated water) affected the proteome of mice bones with increasing PMSIs (from zero to three weeks).

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Tibia

SUBMITTER: Noemi Procopio

LAB HEAD: Noemi Procopio

PROVIDER: PXD017386 | Pride | 2020-04-06

REPOSITORIES: Pride

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Aquatic Decomposition of Mammalian Corpses: A Forensic Proteomic Approach.

Mizukami Haruka H Hathway Bella B Procopio Noemi N

Journal of proteome research 20200416 5

Methods currently available to estimate the <i>postmortem</i> submerged interval (PMSI) of cadavers in water suffer from poor accuracy, being mostly based on morphological examination of the remains. Proteins present within bones have recently attracted more attention from researchers interested in the estimation of the <i>postmortem</i> interval (PMI) in terrestrial environments. Despite the great potential of proteomic methods for PMI estimation, their application to aquatic environments has n ...[more]

PMID: 32242669

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