Persistent changes in the glutamatergic and GABAergic signaling in adolescent rats exposed developmentally to chlorpyrifos

ABSTRACT: Male Sprague Dawley rats were treated daily by oral gavage with either corn oil, chlorpyrifos, or PF-04457845 (selective FAAH inhibitor) from postnatal day10-16. The rats were scarified on postnatal day 38, and brains were collected and stored at -80˚C. Amygdala was isolated from the brain, homogenized the tissue, proteins were quantified, trypsin digested, and analyzed by LC ESI MS/MS.

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Brain

SUBMITTER: Navatha Alugubelly  

LAB HEAD: Russell L.Carr

PROVIDER: PXD017405 | Pride | 2022-08-11

REPOSITORIES: Pride