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The specific localization and function of Cdc42 isoforms

ABSTRACT: Cdc42 is a small GTPase protein whose role in polarity is widely studied. However, in vertebrates there exist 2 isoforms arising due to alternative splicing. The function and localization of these have not been studied with respect to cell polarity and cell migration. We therefore perform a mass spec screen to identify interactors of the isoforms to better understand their cellular functions.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Valentin SABATET

LAB HEAD: Damarys Loew

PROVIDER: PXD017477 | Pride | 2024-01-23

REPOSITORIES: Pride

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