Proteome and Translatome of SARS-CoV-2 infected cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Colon
DISEASE(S): Colon Cancer
SUBMITTER: 
Kevin Klann
LAB HEAD: Christian Münch
PROVIDER: PXD017710 | Pride | 2020-07-20
REPOSITORIES: Pride
Publications
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets.
Bojkova Denisa D Klann Kevin K Koch Benjamin B Widera Marek M Krause David D Ciesek Sandra S Cinatl Jindrich J Münch Christian C
Nature 20200514 7816
A new coronavirus was recently discovered and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection with SARS-CoV-2 in humans causes coronavirus disease 2019 (COVID-19) and has been rapidly spreading around the globe<sup>1,2</sup>. SARS-CoV-2 shows some similarities to other coronaviruses; however, treatment options and an understanding of how SARS-CoV-2 infects cells are lacking. Here we identify the host cell pathways that are modulated by SARS-CoV-2 and show that inhib ...[more]
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