Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Kidney
SUBMITTER: Lei Fang
LAB HEAD: Lei Fang
PROVIDER: PXD017849 | Pride | 2022-05-19
REPOSITORIES: Pride
Wu Wen-Yuan WY Wang Zi-Xuan ZX Li Tu-Shuai TS Ding Xiao-Qin XQ Liu Zhi-Hong ZH Yang Jie J Fang Lei L Kong Ling-Dong LD
Redox biology 20220331
High fructose consumption is a significant risking factor for glomerular podocyte injury. However, the causes of high fructose-induced glomerular podocyte injury are still unclear. In this study, we reported a novel mechanism by which high fructose induced ferroptosis, a newly form of programmed cell death, in glomerular podocyte injury. We performed quantitative proteomic analysis in glomeruli of high fructose-fed rats to identify key regulating proteins involved in glomerular injury, and found ...[more]