PrimPol primase mediates replication traverse of DNA interstrand crosslinks

ABSTRACT: Human cancer cells rely on PRIMPOL primase activity to mediate ICL traverse, sustain DNA synthesis and complete DNA replication

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

SUBMITTER: Fernando Garcia  

LAB HEAD: Javier Munoz

PROVIDER: PXD017951 | Pride | 2021-05-20

REPOSITORIES: Pride