MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity

ABSTRACT: The interaction partners of C. elegans soluble IL-17 signaling components were profiled using IP/MS. In vivo interactions were profiled for ACTL-1-FLAG, PIK-1-Myc, MALT-1::GFP, NFKI-1::GFP and their respective controls. Quantification of NFKI-1::GFP interactions was performed by labelling immunoprecipitated proteins using tandem mass tags.

INSTRUMENT(S):

ORGANISM(S): Caenorhabditis Elegans

SUBMITTER: Mark Skehel  

LAB HEAD: Mario de Bono

PROVIDER: PXD018000 | Pride | 2020-05-27

REPOSITORIES: Pride