Proteome and Crotonylome of normal and leucine deprivation treated AML12 cells

ABSTRACT: Leucine, as a branched amino acid, is not only a substrate for protein synthesis, but also a signaling molecule that affects many biological processes. Lysine crotonylation is a novel post-translational modification in both histone and non-histone proteins. What effect amino acids have on crotonylation remains unclear. Here, we identified a large number of crotonylated proteins and sites affected by leucine deprivation for 2 hours in AML12 cells.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture

SUBMITTER: Zheng Zilong  

LAB HEAD: Zilong Zheng

PROVIDER: PXD018118 | Pride | 2023-05-10

REPOSITORIES: Pride