Mouse kidney glomeruli. Control vs. podocin(R231Q/A268V)

ABSTRACT: Similar to human patients, mice with the compound heterozygous mutation podocin R231Q/A268V, develop a late onset FSGS. Here, we did a proteomics anaylsis of kidney glomeruli before the onset of disease (mice at 3 weeks of age). Analysis of the data reveals that there are no developmental changes in the proteome of compund heterozygous mice.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Kidney

DISEASE(S): Focal Segmental Glomerulosclerosis

SUBMITTER: Martin Hoehne  

LAB HEAD: Thomas Benzing

PROVIDER: PXD018326 | Pride | 2020-05-15

REPOSITORIES: Pride