Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Cell, Blood
DISEASE(S): Acute Leukemia
SUBMITTER: Maria Hernandez-Valladares
LAB HEAD: Frode Berven
PROVIDER: PXD018359 | Pride | 2020-06-12
REPOSITORIES: Pride
Aasebø Elise E Berven Frode S FS Hovland Randi R Døskeland Stein Ove SO Bruserud Øystein Ø Selheim Frode F Hernandez-Valladares Maria M
Cancers 20200604 6
Acute myeloid leukemia (AML) is an aggressive hematological malignancy. Nearly 50% of the patients who receive the most intensive treatment develop chemoresistant leukemia relapse. Although the leukemogenic events leading to relapse seem to differ between patients (i.e., regrowth from a clone detected at first diagnosis, progression from the original leukemic or preleukemic stem cells), a common characteristic of relapsed AML is increased chemoresistance. The aim of the present study was to inve ...[more]