Dataset Information
Proteomic signatures of metronidazole-resistant Trichomonas vaginalis
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Trichomonas Vaginalis
SUBMITTER: 
Kuo-Yang Huang
LAB HEAD: Kuo-Yang Huang
PROVIDER: PXD018522 | Pride | 2021-09-09
REPOSITORIES: Pride
Publications
Proteomic signatures of metronidazole-resistant Trichomonas vaginalis reveal novel proteins associated with drug resistance.
Parasites & vectors 20200601 1
<h4>Background</h4>Trichomoniasis is the most common non-viral sexually transmitted disease caused by the protozoan parasite Trichomonas vaginalis. Metronidazole (MTZ) is a widely used drug for the treatment of trichomoniasis; however, increased resistance of the parasite to MTZ has emerged as a highly problematic public health issue.<h4>Methods</h4>We conducted iTRAQ-based analysis to profile the proteomes of MTZ-sensitive (MTZ-S) and MTZ-resistant (MTZ-R) parasites. STRING and gene set enrichm ...[more]
