Proteomics

Dataset Information

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Salivary proteome in canine pyometra


ABSTRACT: The aims were to explore whether saliva composition could reflect the physiopathological changes occurring in canine pyometra and to identify potential biomarkers of the disease using a high-throughput quantitative proteomic analysis. Saliva samples from six healthy (H) and six bitches with pyometra (P) were analysed using Tandem Mass Tags (TMT) - based approach.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Saliva

DISEASE(S): Uterine Inflammatory Disease

SUBMITTER: Anita Horvatic  

LAB HEAD: Peter David Eckersall

PROVIDER: PXD018692 | Pride | 2020-04-27

REPOSITORIES: Pride

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Publications


The present study evaluated for the first time changes in the saliva proteome in bitches with pyometra through a high-throughput quantitative proteomic analysis. The aims were to explore whether saliva composition could reflect the physiopathological changes occurring in canine pyometra and to identify potential biomarkers of the disease. Saliva samples from six healthy (H) and six bitches with pyometra (P) were analyzed using tandem mass tags-based approach. Additionally, 15 samples were used f  ...[more]

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