Histone modification signatures in mice melanoma progression

ABSTRACT: In the search for the biological mechanisms that underlie melanoma development, we have developed a cellular system that models tumor initiation and transformation from melanocytes to metastatic melanoma cells.. To evaluate histone PTM, we applied a workflow to globally detect histone PTM by mass spectrometry approaches allowing the interrogation of more than 40 PTMs sites and 200 PTMs combinations.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Julia Cunha  

LAB HEAD: Miriam Galvonas

PROVIDER: PXD019313 | Pride | 2021-09-09

REPOSITORIES: Pride