Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Julia Cunha
LAB HEAD: Miriam Galvonas
PROVIDER: PXD019313 | Pride | 2021-09-09
REPOSITORIES: Pride
Azevedo Hátylas H Pessoa Guilherme Cavalcante GC de Luna Vitorino Francisca Nathália FN Nsengimana Jérémie J Newton-Bishop Julia J Reis Eduardo Moraes EM da Cunha Júlia Pinheiro Chagas JPC Jasiulionis Miriam Galvonas MG
Clinical epigenetics 20200824 1
<h4>Background</h4>We have previously developed a murine cellular system that models the transformation from melanocytes to metastatic melanoma cells. This model was established by cycles of anchorage impediment of melanocytes and consists of four cell lines: differentiated melanocytes (melan-a), pre-malignant melanocytes (4C), malignant (4C11-), and metastasis-prone (4C11+) melanoma cells. Here, we searched for transcriptional and epigenetic signatures associated with melanoma progression and m ...[more]