Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Placenta
SUBMITTER: Swati Varshney
LAB HEAD: Eva Dimitriadis
PROVIDER: PXD019331 | Pride | 2021-04-20
REPOSITORIES: Pride
Hypertension (Dallas, Tex. : 1979) 20200831 4
Preeclampsia is a serious pregnancy-induced disorder unique to humans. The etiology of preeclampsia is poorly understood; however, poor placental formation is thought causal. Galectin-7 is produced by trophoblast and is elevated in first-trimester serum of women who subsequently develop preeclampsia. We hypothesized that elevated placental galectin-7 may be causative of preeclampsia. Here, we demonstrated increased galectin-7 production in chorionic villous samples from women who subsequently de ...[more]