Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Jie Luo
LAB HEAD: Jeff Ranish
PROVIDER: PXD019400 | Pride | 2020-05-27
REPOSITORIES: Pride
Patel Avinash B AB Moore Camille M CM Greber Basil J BJ Luo Jie J Zukin Stefan A SA Ranish Jeff J Nogales Eva E
eLife 20191230
Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The <i>Saccharomyces cerevisiae</i> RSC (<u>R</u>emodeling the <u>S</u>tructure of <u>C</u>hromatin) complex, a member of the SWI/SNF chromatin remodeler family, plays critical roles in genome maintenance, transcription, and DNA repair. Here, we report cryo-electron microscopy (cryo-EM) and crosslinking mass spectrometry (CLMS) studies of yeast RSC complex and ...[more]